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. 2022 Jul 7;13:928419. doi: 10.3389/fphar.2022.928419

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Copyright © 2022 Wang, Qu, Chen, Pan, Tang, Hu, Gao, Niu, Liu, Gao and Fang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lactate metabolism-related genes and prognostic analysis of patients with BRCA and THCA. (A) Lactate metabolism-related genes in BRCA and overall survival (OS)-related Lasso regression to screen for prognostic factors. (B) The forest map presents the results of a multivariate Cox regression between genes associated with lactate metabolism in BRCA and OS. (C) Heat map of OS-related independent risk factors in BRCA. (D) Lactate metabolism-related genes in BRCA and PFS-related Lasso regression to screen for prognostic factors. (E) The forest map shows the results of a multivariate Cox regression between lactate metabolism-associated genes in BRCA and PFS. (F) Heat map of PFS-related independent risk factors in BRCA. (G) Lactate metabolism-related genes in THCA and OS-related Lasso regression to screen for prognostic factors. (H) The forest map reveals the results of multivariate Cox regression between lactate metabolism-related genes in THCA and OS. (I) Heat map of OS-related independent risk factors in THCA. (J) Lactate metabolism-related genes in THCA and PFS-related Lasso regression to screen for prognostic factors. (K) The forest map indicates multi-factor Cox regression results of lactate metabolism-related genes and PFS in THCA. (L) Heat map of PFS-related independent risk factors in THCA.