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. 2022 Jul 7;13:928419. doi: 10.3389/fphar.2022.928419

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Copyright © 2022 Wang, Qu, Chen, Pan, Tang, Hu, Gao, Niu, Liu, Gao and Fang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The lactate metabolism score is a good predictor of immune characteristics in thyroid and breast cancers. (A,B) Comparison of receiver operating characteristic (ROC) curves of lactate metabolism score, glycolytic activity in BRCA, and the ability of microsatellite instability (MSI) and tumor mutation burden (TMB) to predict the immune score and immune cytolytic activity (CYT). (C,D) Comparison of ROC curves of lactate metabolism score, glycolytic activity in THCA, and the ability of MSI and TMB to predict the immune score and immune CYT. (E,F) The KEGG enrichment pathways of lactate-related genes in BRCA and THCA.