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Diagram of the experimental design. (A) The structure of Nobiletin (NOB). (B) The mice received YMT at postoperative day 3, OFT at postoperative day 4 and NOR at postoperative day 5 and 6. (C) Another group of mice received NOB i.p. for 7 consecutive days before surgery. The behavioral tests were studies with the same interval as in panel (B). YMT: Y maze test. OFT: open filed test. NOR: novel object recognition.
