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. 2022 Jul 7;13:926381. doi: 10.3389/fneur.2022.926381

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Copyright © 2022 Machegger, Bosque Varela, Kuchukhidze, Steinbacher, Öllerer, Prüwasser, Zimmermann, Pikija, Pfaff, Trinka and Mc Coy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cortical laminar necrosis in acute ischemic stroke (AIS) and status epilepticus (SE). First row: Patient with AIS in territories of right anterior and middle cerebral arteries, with an increased signal in diffusion-weighted imaging (DWI) (A) and decreased signal in apparent diffusion coefficient (ADC) (B). Quantification of DWI and ADC signals was done for the lesion side as compared to the contralateral healthy mirror side. The ratio for DWI lesion/healthy side was 1.70 and the ratio for ADC lesion/healthy side was 0.58. Second row: Patient with SE. The DWI-restricted lesion in the right parieto-occipital region (C,D) was suggestive of peri-ictal MRI abnormalities. In arterial spin labeling (E) and MRI-perfusion with a contrast substance (F), an ictal hyperperfusion in the right parieto-occipital region was observed. The ratio for DWI lesion/healthy side was 1.40 and the ratio for ADC lesion/healthy side was 0.84.