FIGURE 6.

SCFA concentrations and the relative expression of SCFA metabolism related genes. The colonic tissues and faeces were collected from healthy, bacterial-infected, single-dose Pc-treated, FMT-treated, and PcFMT-treated mice 48 h after S. Typhimurium (0.2 mL, 4 × 10⁸ CFU/mouse) infection. (A) SCFA contents (acetate, propionate, butyrate) in the faeces of healthy, bacteria-infected, single-dose Pc-treated, FMT-treated, and PcFMT-treated mice. (B) The transcription levels of the SCFA transporters SMCT1 and MCT1 and the SCFA receptors HDAC and GPR43 in the colonic tissues of different treatment groups. The relative expression was calculated as the ratio of the target gene to the internal reference genes (β-actin and GAPDH). Healthy mice were used as controls. Data are expressed as the means ± SEM, n = 6. *P < 0.05; **P < 0.01; ***P < 0.001.