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. 2022 Jul 7;13:942271. doi: 10.3389/fendo.2022.942271

Table 5.

Coexist interaction of overweight or obesity, excessive gestational weight gain and glucose tolerance status on adverse pregnancy outcomesa.

Pre-pregnancy BMI category(kg/m2) Gestational weight gain category Glucose tolerance status Macrosomia LGA Preterm deliveryb HDP SGA Cesarean section Full term low birth weight Composite outcome
Underweight or Normal (<24.0) As or below recommended One abnormal items 1.00(Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.)
At least two abnormal items 1.52
(1.01,2.29)
1.21
(1.01,1.46)
1.13
(0.83,1.52)
1.84
(1.26,2.70)
0.97
(0.61,1.54)
1.10
(0.94,1.28)
1.24
(0.67,2.29)
1.13
(0.98,1.32)
Above recommended One abnormal items 2.22
(1.49,3.32)
1.63
(1.34,1.98)
0.62
(0.42,0.93)
2.58
(1.74,3.82)
0.85
(0.50,1.44)
1.49
(1.25,1.78)
1.19
(0.56,2.54)
1.55
(1.34,1.84)
At least two abnormal items 3.37
(2.15,5.26)
1.84
(1.44,2.34)
0.75
(0.46,1.22)
2.53
(1.57,4.08)
0.65
(0.30,1.39)
1.37
(1.10,1.71)
0.39
(0.09,1.68)
1.45
(1.17,1.80)
Overweight or Obese (≥24.0) As or below recommended One abnormal items 2.12
(1.19,3.78)
1.50
(1.12,2.02)
0.51
(0.26,1.03)
3.91
(2.29,5.96)
1.24
(0.60,2.60)
1.55
(1.19,2.00)
1.70
(0.69,4.23)
1.61
(1.24,2.09)
At least two abnormal items 2.01
(1.13,3.73)
1.44
(1.12,1.94)
1.00
(0.60,1.67)
4.11
(2.41,6.34)
0.82
(0.34,1.95)
1.42
(1.10,1.83)
0.43
(0.10,1.89)
1.67
(1.28,2.15)
Above recommended One abnormal items 4.48
(2.71,7.4114)
2.7313
(2.040,3.66)
0.83
(0.45,1.53)
3.66
(2.17,6.15)
0.15
(0.02,1.12)
2.20
(1.67,2.90)
0.33
(0.04,2.54)
2.74
(2.04,3.68)
At least two abnormal items 4.52
(2.60,7.84)
3.19
(2.33,4.37)
1.38
(0.80,2.38)
7.60
(4.78,12.08)
0.70
(0.25,1.99)
2.56
(1.89,3.47)
0.27
(0.35,2.11)
3.75
(2.63,5.34)

Data are showed as OR(95%CI).

BMI, body mass index; LGA, large for gestational age; SGA, small for gestational age; HDP: Hypertensive disorders of pregnancy; a For all outcomes except preterm delivery were adjusted for maternal age, gestational age, infant sex, gravity, and parity. b adjusted for on the maternal age, infant sex, gravity, and parity.