TABLE 1.
Identified metabolic biomarkers.
| Number | Name | OPLS-DA (VIP) | OPLS-DA [p(corr)] | remark |
| 1 | L-Glutamate | 2.36931 | 0.946563 | **** |
| 2 | D-Alany1-D-alanine | 2.02014 | 0.921418 | **** |
| 3 | L-Proline | 1.67139 | 0.829538 | **** |
| 4 | sn-Glycerol-3-phosphate | 1.60897 | 0.929770 | **** |
| 5 | 5-Aminopentanoate | 1.59915 | 0.795938 | **** |
| 6 | L-Lysine | 1.40204 | 0.945469 | **** |
| 7 | L-Threonine | 1.28046 | 0.844373 | **** |
| 8 | L-Alanine | 1.12990 | 0.857487 | **** |
| 9 | 5,6-Dihydrouracil | 1.09775 | 0.924627 | **** |
| 10 | L-Serine | 1.06673 | 0.966028 | **** |
| 11 | Lactate | 1.01673 | 0.941555 | **** |
The thresholds of VIP score, p (corr) calculated from OPLS-DA, and p-value calculated from t-test were set to 1.00, 0.50, and 0.05, respectively. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.