Figure 4.

Control mice lack motivation after chronic SCI. (A) Intrinsic motivation was measured by assessing the degree of participation in rehabilitative treadmill training. Mean and standard deviation (vehicle with treadmill training n = 13 and GBP with treadmill training n = 14). (B) Analysis of (A). Variable effects on motivation toward rehabilitative treadmill training in SCI mice administered vehicle and GBP are displayed as coefficients with confidence intervals (Generalized linear mixed effect model for repeated measures *p < 0.05, **p < 0.01, ns not significant, vehicle with treadmill training n = 13 and GBP with treadmill training n = 14 mice). (C) Predicted changes in motivation toward the rehabilitative treadmill training in SCI mice administered vehicle or GBP. Shaded error bands indicate confidence intervals.