Figure 1. Tacrolimus provides protection against dextran sulfate sodium (DSS)-induced colitis in a transforming growth factor (TGF)β expressionindependent manner. A: Graphical representation of the average percentage of body weight change during the experiment is shown. The data are shown as the mean±SD (n=8 mice per group). B: Macroscopic view of colons on day 9 after DSS treatment in tacrolimus- and vehicle-treated mice that were or were not treated with anti-transforming growth factor β (TGFβ) are presented. C: Colon length in tacrolimus- and vehicle-treated mice on day 9 after DSS treatment, with and without anti-TGFβ. **Significantly different at p<0.01 vs. vehicle-treated mice.