Table 6.
Items | Control | Antibiotic | Probiotics | Synbiotics | SEM | P-values |
---|---|---|---|---|---|---|
group | group | group | group | |||
ALT (U/L) | ||||||
65 days of age | 58.79 | 56.28 | 56.81 | 59.15 | 2.369 | 0.782 |
95 days of age | 54.74b | 54.22b | 59.60b | 78.33a | 4.811 | 0.004 |
125 days of age | 51.77 | 48.18 | 50.76 | 48.10 | 3.847 | 0.873 |
ALP (U/L) | ||||||
65 days of age | 148.88 | 164.00 | 134.57 | 155.50 | 8.351 | 0.108 |
95 days of age | 123.63 | 127.17 | 118.50 | 122.83 | 10.524 | 0.951 |
125 days of age | 162.88ab | 197.50a | 142.83b | 123.00b | 13.740 | 0.010 |
α-AMS (U/L) | ||||||
65 days of age | 2260.50a | 1851.40b | 1842.17b | 1852.33b | 76.887 | 0.001 |
95 days of age | 2186.71 | 2074.40 | 2176.80 | 2271.60 | 80.523 | 0.405 |
125 days of age | 2306.00b | 2783.00a | 2438.25ab | 2806.00a | 121.075 | 0.016 |
AST (U/L) | ||||||
65 days of age | 59.75 | 56.40 | 73.71 | 53.83 | 6.181 | 0.129 |
95 days of age | 73.30a | 53.80bc | 47.33c | 63.75ab | 3.606 | <0.0001 |
125 days of age | 65.17a | 47.20b | 49.50b | 67.50a | 5.292 | 0.023 |
CHE (g/L) | ||||||
65 days of age | 534.63a | 540.33a | 420.29b | 548.33a | 16.605 | <0.0001 |
95 days of age | 516.25a | 542.83a | 427.60b | 457.71b | 15.986 | <0.0001 |
125 days of age | 467.67 | 475.25 | 445.50 | 487.25 | 13.724 | 0.203 |
LDH (U/L) | ||||||
65 days of age | 416.75b | 332.20c | 503.67a | 378.17bc | 18.040 | <0.0001 |
95 days of age | 465.71a | 374.43b | 322.67b | 437.67a | 19.825 | <0.0001 |
125 days of age | 475.57a | 383.25b | 383.29b | 411.25ab | 26.291 | 0.042 |
ALB (g/L) | ||||||
65 days of age | 41.23a | 35.54b | 41.21a | 40.50a | 0.643 | <0.0001 |
95 days of age | 40.45 | 39.46 | 40.58 | 40.48 | 0.657 | 0.596 |
125 days of age | 43.86 | 44.53 | 45.18 | 43.93 | 0.915 | 0.677 |
AMM (μmol/L) | ||||||
65 days of age | 167.93 | 159.24 | 203.50 | 189.87 | 14.293 | 0.137 |
95 days of age | 265.37a | 236.36a | 171.86b | 229.62a | 17.090 | 0.005 |
125 days of age | 332.90a | 128.30d | 198.58c | 269.55b | 21.299 | <0.0001 |
TP (g/L) | ||||||
65 days of age | 65.00 | 66.62 | 65.13 | 67.52 | 0.765 | 0.078 |
95 days of age | 73.68ab | 73.68ab | 74.63a | 70.82b | 0.939 | 0.043 |
125 days of age | 72.76a | 68.90b | 73.78a | 73.10a | 0.833 | 0.002 |
UN (mmol/L) | ||||||
65 days of age | 3.10 | 3.20 | 3.18 | 2.87 | 0.341 | 0.901 |
95 days of age | 3.56a | 3.60a | 2.42c | 3.14b | 0.127 | <0.0001 |
125 days of age | 3.47ab | 3.98a | 3.93a | 3.35b | 0.158 | 0.020 |
HDL-C (mmol/L) | ||||||
65 days of age | 0.76b | 0.75b | 0.74b | 0.88a | 0.033 | 0.019 |
95 days of age | 1.07 | 1.11 | 1.05 | 1.01 | 0.036 | 0.292 |
125 days of age | 1.10b | 1.22a | 1.23a | 1.09b | 0.036 | 0.010 |
LDL-C (mmol/L) | ||||||
65 days of age | 1.28b | 1.08c | 1.26b | 1.50a | 0.050 | <0.0001 |
95 days of age | 1.57 | 1.64 | 1.66 | 1.60 | 0.084 | 0.860 |
125 days of age | 1.53 | 1.26 | 1.53 | 1.43 | 0.073 | 0.052 |
TC (mmol/L) | ||||||
65 days of age | 2.37b | 2.12c | 2.31b | 2.53a | 0.053 | <0.0001 |
95 days of age | 2.68 | 2.90 | 2.85 | 2.83 | 0.073 | 0.199 |
125 days of age | 2.78ab | 2.59b | 3.05a | 2.78ab | 0.082 | 0.004 |
TG (mmol/L) | ||||||
65 days of age | 0.49 | 0.48 | 0.49 | 0.53 | 0.034 | 0.734 |
95 days of age | 0.76a | 0.60ab | 0.63ab | 0.51b | 0.047 | 0.009 |
125 days of age | 0.62b | 0.61b | 0.56b | 0.82a | 0.034 | <0.0001 |
GLU (mmol/L) | ||||||
65 days of age | 5.30a | 5.12ab | 5.30a | 4.66b | 0.176 | 0.049 |
95 days of age | 6.40a | 4.66b | 5.18b | 4.78b | 0.246 | <0.0001 |
125 days of age | 4.48 | 4.92 | 4.66 | 4.80 | 0.161 | 0.261 |
Data are presented as means with pooled SEM. Values in the same row with different superscript letters were significantly different (P < 0.05). The replicates per group at 65 and 95 days of age were 8; at 125 days of age, the replicates of the control group, antibiotic group, probiotics group, and synbiotics group were 8, 6, 8, and 6, respectively. ALT, alanine aminotransferase; ALP, alkaline phosphatase; α-AMS, α-amylase; AST, aspartate aminotransferase; CHE, cholinesterase; LDH, lactate dehydrogenase; ALB, albumin; AMM, ammonia; TP, total protein; UN, urea nitrogen; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol; TC, total cholesterol; TG, triglyceride; GLU, glucose.