Table 3.

Energy phenotype. The distinct parameter were taken before (v), after the first 10-pass OHT (n) and after the second 10-pass OHT one week later (nn). The data represent cumulative data from the respective subjects and are expressed as means + s.e.m and as median. The statistics include the t-test and the Cohen`t d test. OCR: oxygen comsumption rate in pmolO2/min; ECAR: extracellular acidification rate in mph/min

	v (n = 6)	n (n = 5)	nn (n = 6)	overall (n = 17)
Respiratory quotient, basal
Mean (SD)	7.01 (4.04)	5.34 (1.48)	2.09 (0.591)	4.78 (3.23)
Median [min, max]	6.09 [1.65, 13.0]	6.28 [3.63, 6.55]	2.12 [1.20, 2.82]	3.82 [1.20, 13.0]
t-test	0.03 nn versus v; 0.382 n versus v; 0.0055 n versus nn
Cohen`s d	1.70 nn versus v; 0.52 n versus v; 3.01 n versus nn
Respiratory quotient, energy demand
Mean (SD)	3.20 (1.21)	2.82 (0.680)	1.48 (0.321)	2.48 (1.10)
Median [min, max]	3.29 [1.50, 5.01]	2.73 [2.22, 3.92]	1.54 [0.95, 1.91]	2.31 [0.95, 5.01]
T-test	0.016 nn versus v; 0.53 n versus v; 0.008 n versus nn
Cohen`s d	1.94 nn versus v; 2.62 n versus nn
Fold increase in OCR, energy demand
Mean (SD)	2.29 (0.52)	2.04 (0.337)	2.41 (0.211)	2.26 (0.387)
Median [min, max]	2.07 [1.97, 3.32]	2.00 [1.69, 2.42]	2.36 [2.13, 2.71]	2.30 [1.69, 3.32]
T-test	0.622 nn versus v; 0.37 n versus v; 0.077 n versus nn
Cohen`s d	0.54 n versus v; 1.327 n versus nn
Fold increase in ECAR, energy demand
Mean (SD)	1.29 (0.343)	1.20 (0.0675)	1.87 (0.340)	1.47 (0.411)
Median [min, max]	1.18 [1.08, 1.98]	1.20 [1.13, 1.29]	1.79 [1.53, 2.37]	1.24 [1.08, 2.37]
T-test	0.014 nn versus v; 0.55 n versus v; 0.004 n versus nn
Cohen`s d	1.69 nn versus v; 2.603 n versus nn