Table 2.
Mitochondrial redox state (NADH/FAD) at 25-min ischemia (ISC) and 20-min reperfusion (REP). TC: time control; IR: ischemia and reperfusion without intervention; IR + CP: IR plus cardioplegia treatment; IR + H: IR plus hypothermia treatment; HCP: and hypothermia plus cardioplegia treatment + IR. N = 6 hearts in each group. Values represent mean ± SE. ∗p < 0.05 compared to TC group; #p < 0.05 compared to IR group; $p < 0.05 compared to IR + CP group.
| Time (min) | TC | IR | IR + CP | IR + H | IR + HCP |
|---|---|---|---|---|---|
| NADH (AFU) | |||||
| 25-min ISC | 1.30 ± 0.04 | 1.45 ± 0.03∗ | 1.50 ± 0.03∗ | 1.92 ± 0.07∗#$ | 1.83 ± 0.06∗#$ |
| 20-min REP | 1.30 ± 0.06 | 1.26 ± 0.04 | 1.27 ± 0.11 | 1.41 ± 0.10 | 1.40 ± 0.11 |
| FAD (AFU) | |||||
| 25-min ISC | 0.24 ± 0.01 | 0.26 ± 0.04 | 0.21 ± 0.02 | 0.21 ± 0.01 | 0.21 ± 0.02 |
| 20-min REP | 0.24 ± 0.02 | 0.24 ± 0.04 | 0.25 ± 0.03 | 0.24 ± 0.02 | 0.23 ± 0.02 |