Table 1.
Summary of baseline s/mIPSC characteristics and PPR from all recorded CeA neurons in this study.
| Frequency (HZ) | Amplitude (pA) | Rise time (ms) | Decay time (ms) | n | |
|---|---|---|---|---|---|
| sIPSCs | |||||
| Naïve | 1.41 ± 0.14 | 73.6 ± 4.4 | 2.68 ± 0.05 | 8.95 ± 0.59 | 41 |
| Dep. | 1.73 ± 0.15 | 63.7 ± 3.2 | 2.81 ± 0.06 | 9.13 ± 0.60 | 42 |
| WD | 2.12 ± 0.33 | 72.7 ± 5.8 | 2.53 ± 0.06 | 7.36 ± 0.51 | 23 |
| mIPSCs | |||||
| Naïve | 1.13 ± 0.37 | 71.3 ± 5.6 | 2.5 ± 0.15 | 7.0 ± 0.9 | 8 |
| PPR | |||||
| Naïve | 1.08 ± 0.2 | 8 | |||
| Dep | 0.82 ± 0.1 | 10 | |||
| WD | 0.71 ± 0.1 | 12 | |||
A one-way ANOVA reavealed a main effect of chronic alcohol exposure on sIPSC frequencies (F (2,103); P = 0.0485) and rise times (F (2, 103) = 5.015; P = 0.0083).
Data for each condition were derived from ≥5 animals and n denotes the number of recorded cells. Note that these recordings have been performed with 0.05% DMSO in the bath solution.