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. Author manuscript; available in PMC: 2022 Jul 21.
Published in final edited form as: Pediatrics. 2020 Jan;145(1):e20191930. doi: 10.1542/peds.2019-1930

TABLE 4.

Incidence Rates per 100 000 Person-Years for Single Test and Combination Test Results in Participants Treated and Untreated for LTBI

Test Result All Participants
Untreated
Treateda
No. Cases IRb (95% CI) No. Cases No. Participants No. PY No. Cases No. Participants No. PY

Single test results
 TST+ 2 49 (12–197) 1 630 2639 1 328 1414
 TST− 2 19 (5–75) 0 2604 10 545 2 31 122
 QFT-GIT+ 3 200 (65–620) 1 124 524 2 231 976
 QFT-GIT− 1 8 (1–54) 0 3088 12 563 1 128 560
 T-SPOT+ 2 189 (47–755) 1 78 333 1 173 726
 T-SPOT− 2 15 (4–60) 0 3082 12 514 2 182 792
Combination test results
 TST+ and IGRA+ 2 154 (39–616) 1 97 413 1 209 885
 TST+ and IGRA− 0 0 0 533 2226 0 119 528
 TST− and IGRA+ 1 389 (55–2762) 0 33 135 1 30 121
 TST− and IGRA− 1 10 (1–68) 0 2571 10 410 1 NA NA

IR, incidence rate; NA, not available; PY, person-years; −, negative; +, positive.

a

Completed LTBI treatment or was on LTBI treatment when diagnosed with tuberculosis.

b

Number of tuberculosis cases per 100 000 person-years.