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. Author manuscript; available in PMC: 2022 Jul 21.
Published in final edited form as: Nature. 2021 Sep 1;597(7875):285–289. doi: 10.1038/s41586-021-03856-x

Fig. 2. piRNAs are more selective than miRNAs.

Fig. 2.

a, Schematic of guide RNAs used. b, Fraction of target RNAs bound by hAgo2-guide, EfPiwi-guide, and Siwi-guide RNA complexes at equilibrium versus protein-guide concentration. c, Release rates of g2-g8 complementary target protein-guide RNA complexes. d, Release of 32P-labeled target RNAs from indicated protein-guide complexes in the presence of excess unlabeled target RNA over time. In b-c n=3 independent experiments, data are mean ± s.d.