TABLE 1.
Seropositivity of mice passively immunized with anti-CspZ-YA IgGs followed by the infection of B. burgdorferi
| Characteristic | Data from mice inoculated with: |
||||||
|---|---|---|---|---|---|---|---|
| PBS | Rabbit IgG |
Mouse IgG |
|||||
| Irr. rab. IgGc | CspZ-YA IgG (total) | CspZ-YA IgG (non-FH-binding sites) | Irr. ms. IgGd | 1139 | 1193 | ||
| Infected with I. scapularis nymphs carrying B. burgdorferi 5A4 | Nob | Yes | Yes | Yes | Yes | Yes | Yes |
| Positive ratea | 0/5 | 5/5e | 1/5 | 5/5e | 5/5e | 1/5 | 0/5 |
a
Seropositive rate, the number of mice with sera yielding the levels of IgG against C6 peptides greater than the threshold (mean ± 3-fold standard deviation of the C6 IgG levels derived from the PBS-inoculated, uninfected mice).
b
Uninfected mice.
c
Irrelevant rabbit IgG, anti-green fluorescence protein of rabbit IgG.
d
Irrelevant mouse IgG, anti-green fluorescence protein of mouse IgG.
e
Positive rates significantly greater than those of the uninfected mice determined by two-tailed Fisher test.