TABLE 2.
Infectivity in neonatal mice inoculated with 5 × 105 C. parvum oocysts after treatment in an HRAP at an HRT of 3 days (group A) and 10 days (group B)
| Time p.i. and mouse groupa | % Infectivity (no. of mice infected/no. of mice inoculated) | Intensity of infection (105 oocysts/ml, μ ± SE) | % Reduction of infection |
|---|---|---|---|
| 6 days | |||
| A | 40.0 (20/50)***b | 0.31 ± 0.12*** | 97.1 |
| B | 20.5 (8/39)*** | 0.21 ± 0.13*** | 98.0 |
| C | 100.0 (40/40) | 10.56 ± 1.28 | 0 |
| D | 0 (0/9) | ||
| 10 days | |||
| A | 5.0 (2/48)*** | 0.01 ± 0.01*** | 99.9 |
| B | 12.5 (5/40)*** | 0.11 ± 0.04*** | 99.9 |
| C | 100.0 (40/40) | 15.59 ± 1.31 | 0 |
| D | 0 (0/10) |
a
Group C, control group infected with oocysts that had been stored in a refrigerator at 4°C; group D, uninfected mice used to check for accidental infection during the experiment.
b
***, P < 0.001.