FIG 2.

NanoString data representing the most highly expressed bacterial genes from bacteria recovered from the bronchoalveolar lavage (BAL) fluid in a mouse pneumococcal pneumonia or a septicemia model (blood). (A) Infected mice were euthanized at different time points postinoculation. BAL fluid and blood were collected from each mouse. CFU are reported for each condition tested. Each bar represents data from pools of 5 mice. (B) The 30 most highly expressed genes from pneumococci recovered from mouse BAL fluid at 9 h postinfection. (C) The 30 most highly expressed genes from pneumococci recovered from blood collected 2 days after lung infection. (D) Venn diagram representing the most highly transcribed shared pneumococcal genes under all five conditions (three colonization time points, blood, and BAL fluid). D1, D3, and D7 represent sample collection on days 1, 3, and 7, respectively.