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. 2022 Jan 2;24(2):299–307. doi: 10.1002/ejhf.2405

Figure 1.

EJHF-2405-FIG-0001-c

Restricted cubic splines of the association between selenium concentrations and the outcomes. (A) The association between and selenium concentration and the composite endpoint. As can be observed in the figure, subjects with selenium concentrations >110 µg/L had lower risk of mortality or new‐onset HF, while those with selenium concentrations <75 µg/L had an increased risk. Of note, 110 µg/L is the median selenium value of the group with high selenium status, while selenium concentrations <75 µg/L are considered in the range of selenium deficiency. (B) The association between and selenium concentration and all‐cause mortality. (C) The association between and selenium concentration and new onset heart failure. These association has similar trend as with the composite endpoint.