Liver abnormalities were not observed in Keap1FA/–::Nrf2SA/SA mice. (A) Masson’s trichrome staining of Keap1+/+::Nrf2+/+, Keap1+/+::Nrf2SA/SA, Keap1FA/FA::Nrf2+/+, Keap1FA/FA::Nrf2SA/SA, Keap1FA/–::Nrf2+/+, and Keap1FA/–::Nrf2SA/SA mouse livers; (B) mRNA levels of keratin 19 and albumin in the liver. Hprt was used as the internal control. The mRNA levels in the Keap1+/+::Nrf2+/+ mice were set to 1. The bar graphs show the means ± SD. Significance was determined by one-way ANOVA with Tukey’s multiple-comparison test.