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. 2014 Jun;184(6):1890–1899. doi: 10.1016/j.ajpath.2014.02.017

Figure 4.

Figure 4

HIF-1α KO mouse developed normal retina, liver, kidney, and brain. A: Toluidine blue staining, lectin staining, and in vivo fluorescein angiography show normal retinal histology and retinal blood vessels in WT mice. HIF-1α KO mouse had a similar phenotype as in WT. B: Gross microsections stained with H&E show a similar phenotype between normoxic WT and HIF-1α KO mice of liver, kidney, and brain. GCL, ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; IS, inner segment; ONL, outer nuclear layer; OPL, outer plexiform layer; and OS, outer segment of photoreceptors.