Supplemental Figure S3.

RNA profiling of peripheral blood mononuclear cells (PBMCs) from tuberculosis (TB)-infected and TB/HIV–co-infected patients using quantitative real-time PCR. A–H: mRNA expression of selected immune molecules in lymph node tissues. Data are expressed as medians ± ranges. n = 8 TB-infected patients (white bars); n = 8 TB/HIV–co-infected patients (light gray bars); n = 3 HIV-negative controls 4 HIV-positive controls (dark gray bars). ∗P < 0.05 (Kruskal-Wallis and Dunn multiple comparisons tests). Arg-1, arginase-1; Ctrl, controls; eNOS, endothelial nitric oxide synthase; IDO, indoleamine 2,3-dioxygenase; iNOS, inducible nitric oxide synthase; LAG-3, lymphocyte activated gene-3; SOCS-3, suppressor of cytokine signaling-3; TIM-3, T-cell immunoglobulin mucin-3.