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Mean 24-hour urine creatinine clearance (mL/min/1.73 m2) between the two groups at baseline and after receiving cisplatin. A significant difference was found in mean 24-hour urine creatinine clearance between the two groups after receiving cisplatin; the mean 24-hour urine creatinine clearances were 67.4 ± 30.6 mL/min/1.73 m2 in the placebo group, and 96.4 ± 45.5 mL/min/1.73 m2 in the mannitol group (P value = .03).
