Table 2.
Univariate and multivariate linear regressions using BASDAI and ASDAS-CRP as dependent variables.
| Univariate linear regressions | Multivariate linear regressions | |||||
|---|---|---|---|---|---|---|
| Standard coefficient (B) | Regression coefficient (95% CI) | P value | Standard coefficient (B) | Regression coefficient (95% CI) | P value | |
| BASDAI | (n = 420) | |||||
| Axial SpA with late onset (n = 448) | 0.10 | 0.59 (0.07; 1.11) | 0.03 | 0.02 | 0.10 (–0.54; 0.74) | 0.76 |
| Age (n = 448) | 0.13 | 0.02 (0.01; 0.03) | 0.01 | 0.12 | 0.02 (0.001; 0.03) | 0.04 |
| Male gender (n = 448) | –0.10 | –0.40 (–0.79; –0.02) | 0.04 | –0.09 | –0.37 (–0.77; 0.30) | 0.07 |
| Chinese ethnicity (n = 448) | 0.01 | 0.20 (–1.45; 1.85) | 0.81 | |||
| Smoking status (n = 445) | 0.07 | 0.34 (–0.09; 0.78) | 0.12 | |||
| Regular alcohol use (n = 440) | 0.09 | 0.62 (–0.04; 1.29) | 0.06 | 0.11 | 0.82 (0.13; 1.51) | 0.02 |
| Family history of SpA (n = 434) | 0.01 | 0.06 (–0.40; 0.52) | 0.80 | |||
| HLA-B27 positivity (n = 428) | –0.15 | –0.77 (–1.26; –0.28) | 0.002 | –0.14 | –0.73 (–1.22; –0.23) | 0.004 |
| Current c-DMARD therapy (n = 443) | 0.01 | 0.05 (–0.36; 0.46) | 0.81 | |||
| Radiological AS (n = 432) | 0.01 | 0.02 (–0.37; 0.41) | 0.91 | |||
| ASDAS-CRP | (n = 406) | |||||
| Axial SpA with late onset (n = 438) | 0.09 | 0.21 (–0.01; 0.44) | 0.06 | 0.10 | 0.25 (0.01; 0.48) | 0.04 |
| Age (n = 438) | 0.07 | 0.004 (–0.001; 0.01) | 0.14 | |||
| Male gender (n = 438) | 0.00 | –0.001 (–0.17; 0.17) | 1.00 | |||
| Chinese ethnicity (n = 438) | –0.004 | –0.03 (–0.73; 0.67) | 0.93 | |||
| Smoking status (n = 436) | 0.10 | 0.19 (0.01; 0.38) | 0.04 | 0.07 | 0.14 (–0.07; 0.34) | 0.19 |
| Regular alcohol use (n = 431) | 0.11 | 0.34 (0.06; 0.62) | 0.02 | 0.08 | 0.26 (–0.06; 0.57) | 0.11 |
| Family history of SpA (n = 427) | –0.001 | –0.002 (–0.20; 0.20) | 0.99 | |||
| HLA-B27 positivity (n = 423) | –0.09 | –0.19 (–0.40; 0.02) | 0.08 | –0.10 | –0.21 (–0.43; 0.002) | 0.052 |
| Current c-DMARD therapy (n = 436) | 0.04 | 0.07 (–0.11; 0.25) | 0.43 | 0.13 | 0.22 (0.05; 0.40) | 0.01 |
| Radiological AS (n = 425) | 0.13 | 0.22 (0.06; 0.39) | 0.01 | |||
AS = ankylosing spondylitis, ASDAS-CRP = Ankylosing Spondylitis Disease Activity Score based on CRP, BASDAI = Bath Ankylosing Spondylitis Disease Activity Index, c-DMARD = conventional disease modifying antirheumatic drug, CI = confidence interval, HLA = human leukocyte antigen, n = number, SpA = spondyloarthritis.