Table 5.
Univariate and multivariate linear regressions using mSASSS and radiological AS as dependent variables.
| Univariate linear regressions | Multivariate linear regressions | |||||
|---|---|---|---|---|---|---|
| Standard coefficient (B) | Regression coefficient (95% CI) | P value | Standard coefficient (B) | Regression coefficient (95% CI) | P value | |
| mSASSS | (n = 370) | |||||
| Axial SpA with late onset (n = 422) | 0.12 | 6.06 (1.40; 10.72) | 0.01 | –0.12 | –5.81 (–10.75; –0.87) | 0.02 |
| Age (n = 422) | 0.44 | 0.58 (0.47; 0.69) | <0.001 | 0.51 | 0.68 (0.55; 0.81) | <0.001 |
| Male gender (n = 422) | 0.24 | 8.62 (5.25; 11.99) | <0.001 | 0.20 | 7.12 (3.69; 10.54) | <0.001 |
| Chinese ethnicity (n = 422) | 0.06 | 8.49 (–5.90; 22.88) | 0.25 | |||
| Body weight (n = 383) | 0.10 | 0.13 (0.001; 0.26) | 0.05 | 0.04 | 0.06 (–0.06; 0.17) | 0.34 |
| Smoking status (n = 421) | 0.21 | 8.30 (4.54; 12.06) | <0.001 | 0.08 | 3.18 (–0.58; 6.92) | 0.097 |
| Regular alcohol use (n = 415) | 0.09 | 5.72 (–0.17; 11.62) | 0.06 | –0.03 | –1.50 (–6.90; 3.91) | 0.59 |
| Family history of SpA (n = 408) | –0.05 | –2.19 (–6.40; 2.03) | 0.31 | |||
| HLA-B27 positivity (n = 408) | 0.02 | 0.66 (–3.68; 4.99) | 0.77 | |||
| ASDAS-CRP (n = 411) | 0.12 | 2.53 (0.52; 4.55) | 0.01 | 0.07 | 1.40 (–0.38; 3.17) | 0.12 |
| Radiological AS (n = 421) | 0.31 | 10.96 (7.67; 14.24) | <0.001 | 0.22 | 8.14 (4.95; 11.34) | <0.001 |
| Univariate logistic regression | Multivariate logistic regression | |||||
| Odds ratio | 95% CI | P value | Odds ratio | 95% CI | P value | |
| Radiological AS | (n = 407) | |||||
| Axial SpA with late onset (n = 439) | 0.60 | 0.36; 1.00 | 0.05 | 0.65 | 0.37; 1.16 | 0.14 |
| Age (n = 439) | 1.01 | 0.99; 1.02 | 0.45 | |||
| Male gender (n = 439) | 1.77 | 1.20; 2.60 | 0.004 | 1.25 | 0.81; 1.93 | 0.31 |
| Chinese ethnicity (n = 439) | 0.63 | 0.11; 3.46 | 0.59 | |||
| Body weight (n = 396) | 1.00 | 0.98; 1.01 | 0.55 | |||
| Smoking status (n = 437) | 2.76 | 1.73; 4.40 | <0.001 | 1.84 | 1.08; 3.14 | 0.03 |
| Regular alcohol use (n = 431) | 4.92 | 2.01; 12.00 | <0.001 | 3.43 | 1.26; 9.37 | 0.02 |
| Family history of SpA (n = 425) | 0.91 | 0.58; 1.45 | 0.70 | |||
| HLA-B27 positivity (n = 424) | 2.09 | 1.28; 3.41 | 0.003 | 2.21 | 1.31; 3.76 | 0.003 |
| ASDAS-CRP (n = 426) | 1.35 | 1.08; 1.70 | 0.01 | 1.37 | 1.07; 1.75 | 0.01 |
AS = ankylosing spondylitis; ASDAS-CRP = ankylosing spondylitis disease activity score based on CRP; CI = confidence interval; HLA = human leukocyte antigen; mSASSS = modified stoke ankylosing spondylitis spinal score; n = number; SpA = spondyloarthritis.