Table 3.

Comparison of characteristics between groups with or without trauma-induced thrombotic microangiopathy-like syndrome using univariate analysis.

Factors	Non-t-TMAS group (n = 1144)	t-TMAS group (n = 20)	P-value
Sex [female], %	283 (24.7)	6 (30.0)	.604
Mechanism of trauma [penetrating], %	47 (4.1)	0 (0.0)	1.000
Age, yrs	58.2 ± 17.9	71.0 ± 16.8	.000*
ISS	18.4 ± 9.9	23.9 ± 9.2	.007*
On arrival CPK, U/L	839.3 ± 3705.6	811.5 ± 945.5	.065*
LDH, U/L	466.9 ± 375.5	826.9 ± 1078.9	.170*
Myoglobin, ng/mL	1120.6 ± 1675.7	3043.7 ± 3153.4	.000*
Lactate, mmol/L	3.2 ± 2.5	5.8 ± 4.4	.002*
D-dimer, µg/mL	45.7 ± 45.3	74.2 ± 53.2	.124*
CK-MB, ng/mL	13.2 ± 68.8	15.3 ± 15.8	.003*
Day 2 CPK, U/L	2510.0 ± 6841.3	2706.2 ± 1872.5	.004*
LDH, U/L	518.4 ± 575.1	1192.5 ± 1301.3	.000*
Myoglobin, ng/mL	875.3 ± 1606.3	2924.7 ± 3608.2	.063*
Lactate, mmol/L	2.5 ± 2.3	4.1 ± 4.4	.033*
Transfused RBC within 24 h (units)	2.4 ± 4.2	8.7 ± 5.4	.000*
AIS (head) =3	489 (42.7%)	4 (20.0%)	.041
AIS (chest) =3	400 (35.0%)	14 (70.0%)	.001
AIS (abdomen) =3	120 (10.5%)	5 (25.0%)	.054
AIS (pelvis) =3	109 (9.5%)	6 (30.0%)	.010
AIS (extremity) =3	166 (14.5%)	3 (15.0%)	1.000
AIS (C-spine) =3	86 (7.5%)	1 (5.0%)	1.000
AIS (T-spine) =3	31 (2.7%)	0 (0%)	1.000
AIS (L-spine) =3	33 (2.9%)	1 (5.0%)	.450
AIS (head =3, others	331 (28.9%)	1 (5.0%)	.019
Sum AIS (head)	3.56 ± 4.68	1.75 ± 3.26	.085*
Sum AIS (chest)	2.30 ± 3.29	5.05 ± 4.22	.001*
Sum AIS (abdomen)	0.93 ± 1.88	2.35 ± 3.27	.004*
Sum AIS (pelvis)	0.52 ± 1.22	1.55 ± 2.19	.005*
Sum AIS (extremity)	2.00 ± 3.51	2.50 ± 3.35	.313*

AIS = abbreviated injury scale, CK-MB = creatine kinase-myocardial band, CPK = creatinine phosphokinase, ISS = injury severity score, LDH = lactate dehydrogenase, TMAS = thrombotic microangiopathy-like syndrome.

^*Statistical significance was assessed using the Mann–Whitney U test.