Table 3. Twenty-two hub targets.

NO.	Hub target	Betweenness centrality	Closeness centrality	Degree
1	GAPDH	0.069492108	0.795774648	168
2	TP53	0.040729912	0.784722222	165
3	AKT1	0.039453643	0.771331058	160
4	MYC	0.02413519	0.736156352	146
5	ALB	0.044293226	0.736156352	145
6	EGFR	0.015531628	0.70846395	134
7	MAPK3	0.01953981	0.70846395	134
8	VEGFA	0.017537919	0.704049844	133
9	CASP3	0.011495283	0.704049844	132
10	STAT3	0.011020537	0.701863354	131
11	CCND1	0.013690985	0.691131498	128
12	JUN	0.011489939	0.695384615	128
13	PTEN	0.013589929	0.68902439	126
14	EGF	0.014214947	0.691131498	126
15	IL6	0.01571605	0.691131498	126
16	MAPK1	0.014283335	0.68902439	125
17	MAPK8	0.014546931	0.684848485	124
18	HRAS	0.009985322	0.682779456	122
19	SRC	0.011244283	0.678678679	121
20	TNF	0.007928097	0.672619048	117
21	ESR1	0.012107136	0.664705882	114
22	HSP90AA1	0.011944643	0.660818713	113