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P301S mice show early postnatal impairment in hippocampus-dependent nest building. P301S mice showed significantly lower scores of nest building at 4 weeks of age (***p < 0.0001). Data are mean ± SEM. n = number of animals, indicated in the bar graphs. Mann–Whitney test for not normally distributed data: *p < 0.05; **p < 0.01; ***p < 0.001.
