Table 2.
Multivariable HRs for association between predictive variables and generalization.
| Predictive variables | Development cohort | Validation cohort | ||
|---|---|---|---|---|
| HR (95% CI) | P-Value | HR (95% CI) | P-value | |
| Sex | ||||
| Male | 1 | 1 | ||
| Female | 1.45 (0.94-2.24) | 0.10 | 1.27 (0.62-2.62) | 0.52 |
| Onset age | 1.02 (1.01-1.04) | <0.001 | 1.05 (1.02-1.07) | <0.001 |
| RNS findings | ||||
| Normal | 1 | 1 | ||
| Abnormal | 2.80 (1.67-4.70) | <0.001 | 5.44 (2.33-12.70) | <0.001 |
| AChR-Ab | ||||
| Seronegative | 1 | 1 | ||
| Seropositive | 2.42 (1.00-5.88) | 0.05 | 3.27 (0.97-10.96) | 0.06 |
| Thymic status | ||||
| Normal | 1 | 1 | ||
| Thymic hyperplasia | 1.52 (0.83-2.79) | 0.17 | 1.33 (0.49-3.58) | 0.57 |
| Thymoma | 1.84 (1.10-3.07) | 0.02 | 2.72 (1.20-6.62) | 0.03 |
RNS, repetitive nerve stimulation; AChR-Ab, acetylcholine receptor antibody; m, month.