Table 2.
Diagnostic Accuracy of C-Reactive Protein for Childhood TB
| Cut-off | Sensitivity n/N % (95% CI) |
Specificity n/N % (95% CI) |
|---|---|---|
| Confirmed TB versus Unlikely TB | ||
| 10 mg/L | 31/62 50.0% (37.0–63.0) |
88/139 63.3% (54.7-71.3) |
| 5 mg/L | 35/62 56.5% (43.3–69.0) |
75/139 54.0% (45.3–62.4) |
| CRS | ||
| 10 mg/L | 73/193 37.8% (31.0–45.1) |
88/139 63.3% (54.7–71.3) |
| 5 mg/L | 87/193 45.1% (37.9–52.4) |
75/139 54.0% (45.3–62.4) |
| MRS | ||
| 10 mg/L | 31/62 50.0% (37.0–63.0) |
177/270 65.6% (59.6–71.2) |
| 5 mg/L | 35/62 56.5% (43.3–69.0) |
154/270 57.0% (50.9–63.0) |
Abbreviations: CRS, composite reference standard; MRS, microbiological reference standard; TB, tuberculosis.