TABLE 2.
Summary of clinical trials of ginsenosides interventions in cerebarl ischemic stroke patients.
Gensinosides | Model | Sample sizes | Inclusion criteria | Evaluaive critera | Results | References |
---|---|---|---|---|---|---|
Rd | Acute ischaemic stroke | Ginsenoside Rd group (n = 290) placebo group (n = 96) | 1) 18–75 years of age; 2) had received a clinical diagnosis of primary acute ischaemic stroke and were able to receive the study drug within 72 h after the onset of symptoms; 3) had a score of 5–22 on the NIHSS | NIHSS BI | Ginsenoside Rd improved the NIHSS and mRs scores, and had an acceptable adverse event profile. | Liu et al. (2012) |
Rd | Acute ischaemic stroke | Ginsenoside-Rd 10 mg (n = 65) ginsenoside-Rd 20 mg (n = 67) placebo group (n = 67) | 1) between 18 and 75 years of age; 2) had a clinical diagnosis of primary acute ischaemic stroke with an onset of the first episode within the previous 72 h; 3) had a score of 5–22 on the NIHSS | NIHSS BI mRs | Ginsenoside Rd improved NIHSS scores at 15 days, no significance of BI and mRs scores at 15 and 90 days. | Liu et al. (2009) |
NIHSS, national institutes of health stroke scale; mRs, modified Rankin scalel; BI, barthel index.