Table 4. Hazard/Subhazard ratio of outcomes in statin users in comparison to nonusers.
Outcome | Hazard ratio | 95% confidence interval | p-value |
---|---|---|---|
Secondary analysis | |||
Propensity score matched cohort (81,146 statin users and 81,146 nonusers) | |||
Incident CKD | 1.20 | 1.16–1.25 | <0.001 |
Incident Diabetes with ophthalmic manifestations | 1.35 | 1.26–1.44 | <0.001 |
Incident Diabetes with neurological manifestations | 1.19 | 1.15–1.24 | <0.001 |
Propensity score matched cohort with death as a competing risk factor (81,146 statin users and 81,146 nonusers) | |||
Incident CKD | 1.13* | 1.09–1.17 | <0.001 |
Incident Diabetes with ophthalmic manifestations | 1.28* | 1.20–1.37 | <0.001 |
Incident Diabetes with neurological manifestations | 1.19* | 1.15–1.24 | <0.001 |
Post-Hoc analysis | |||
Intensive cholesterol lowering statin users in comparison to nonusers in the overall cohort with death as a competing risk factor (38,823 statin users and 110,195 active comparators) | |||
Incident CKD | 1.57* | 1.51–1.64 | <0.001 |
Incident Diabetes with ophthalmic manifestations | 1.71* | 1.59–1.83 | <0.001 |
Incident Diabetes with neurological manifestations | 1.30* | 1.24–1.36 | <0.001 |
*Subhazard ratio