Table 1.
Spearman's correlation of gut microbiota and indices of liver function.
| Gut bacteriaa | AST | ALT | ALP | |||
|---|---|---|---|---|---|---|
| r | p | r | p | r | p | |
| Akkermansia muciniphila | 0.8167 | 0.0108 | 0.7833 | 0.0172 | 0.0333 | 0.9484 |
| Bifidobacterium pseudolongum | 0.0714 | 0.8820 | 0.0857 | 0.9194 | 0.1429 | 0.7825 |
LEfSe analysis showed that the relative abundance of Akkermansia muciniphila and Bifidobacterium pseudolongum were higher in the SVP group than in the Con and G-CK + SVP groups. AST, aspartate transaminase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; Con, control; SVP, sodium valproate (500 mg/kg, twice daily); G-CK, ginsenoside compound K (320 mg/kg, once daily). Bold indicates correlation.