Table 2.
Spearman's correlation of pathways and indices of liver function.
| Pathwaysa | AST | ALT | ALP | |||
|---|---|---|---|---|---|---|
| r | p | r | p | r | p | |
| Fatty acid biosynthesis | −0.7000 | 0.0433 | −0.7500 | 0.0255 | −0.1879 | 0.6073 |
| Lipid biosynthesis | −0.7000 | 0.0433 | −0.7500 | 0.0255 | −0.2606 | 0.4697 |
| Propanoate metabolism | −0.4167 | 0.2696 | −0.1667 | 0.6777 | −0.0667 | 0.8651 |
| Histidine metabolism | 0.2500 | 0.5206 | 0.1333 | 0.7435 | −0.2121 | 0.5603 |
| Glycolysis/gluconeogenesis | −0.8667 | 0.0045 | −0.8333 | 0.0083 | 0.0182 | 0.9730 |
| Pyruvate metabolism | −0.8167 | 0.0108 | −0.8000 | 0.0138 | −0.1152 | 0.7589 |
| Fructose and mannose metabolism | 0.2000 | 0.6134 | 0.4000 | 0.2912 | 0.0424 | 0.9184 |
Overlapped differential pathways between SVP vs. Con and G-CK + SVP vs. SVP estimated. AST, aspartate transaminase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; Con, control; SVP, sodium valproate (500 mg/kg, twice daily); G-CK, ginsenoside compound K (320 mg/kg, once daily). Bold indicates correlation.