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. 2022 Feb 28;27(4):369–386. doi: 10.1111/tmi.13733

TABLE 2.

Individual study estimates of the unadjusted and adjusted odds ratios of active tuberculosis comparing DM prevalence in TB cases and non‐TB controls in sub‐Saharan Africa

First author, (year) Method of DM diagnosis Number (%) of TB cases with DM Number (%) of non‐TB controls with DM Unadjusted OR of active TB (95% CI) Adjusted OR of active TB (95% CI)
Kubjane et al. (2020) [21] FBG, HbA1c, self‐reported

At enrolment: 49 (11.9)

After follow‐up: 28 (9.3)

38 (8.7)

27 (8.1)

Not reported

2.8 (1.5–5.3) a

3.3 (1.5–7.3)

Sinha et al. (2018) [25] RBG, self‐reported

>1 TB symptom b

>2 TB symptoms

>3 TB symptoms

Not reported Not reported

1.36 (1.11–1.67)

1.47 (1.13–1.91)

1.69 (1.11–2.57) a

Lawson et al. (2017) [26] HbA1c, self‐reported 26 (23.0) 36 (12.1) 2.39 (1.35–4.24) 3.10 (1.62–5.94) a
Boillat‐Blanco et al. (2016) [22]

FCG

OGTT

HbA1c

24 (4.5)

36 (6.8)

49 (9.3)

6 (1.2)

15 (3.1)

11 (2.2)

4.2 (1.7–10.3)

2.9 (1.5–5.4)

6.5 (3.3–12.9)

10.6 (3.2–4.1) c

3.7 (1.6–8.3)

10.7 (4.5–26) a

Senkoro et al. (2016) [23] Self‐reported 4 (2) 45 (1) 3.1 (0.6–16.4) 3.4 (0.8–14.2) a
Bailey et al. (2016) [27] RBG 15 (3.5) 712 (1.8) Not reported 2.15 (1.17–3.94) a
Haraldsdottir et al. (2015) [24] RBG, FBG, registered at DM clinic 3 (2.8) 11 (2.1) Not reported 0.88 (0.17–4.58) a
Bates et al. (2012) [28] DM as admission diagnosis to hospital 4 (20.0) 15 (5.9) 4.00 (1.19–13.5) 6.57 (1.71–25.30) a
Faurholt‐Jepsen et al. (2011) [20] FBG and OGTT 134 (16.7) 33 (9.4) 2.2 (1.5–3.4)

HIV −: 2.14 (1.32–3.46) a

HIV +: 2.05 (0.68–6.29)

Abbreviations: DM, diabetes mellitus; TB, tuberculosis; OR, odds ratio; FBG, fasting blood glucose; HbA1c, glycosylated haemoglobin; RBG, random blood glucose; FCG, fasting capillary glucose; OGTT, oral glucose tolerance test.

a

These are the ORs that were included in the main meta‐analysis.

b

The number of cases and controls was not reported by the study authors.

c

This is an incorrect confidence interval that was reported by the study authors.