Figure 2.

Examples of the quality of the final nuclear and electron densities, shown as meshworks contoured at 1.5 σ and colored in blue and red, respectively. (A) Pairing between A57 and G64. (B) A70 with 2′-OH in the phosphate orientation. (C) C67 with associated D₂O molecules. (D) G61 with 2′-OH in the base orientation. (E) A54 with 2′-OH in the sugar orientation. (F) G69 with associated D₂O molecules. Carbon, oxygen, nitrogen, phosphorus, hydrogen and deuterium atoms are colored in green, red, blue, orange, white and black, respectively, and residues and water molecules are labeled. Figure panels were made using PyMOL (The PyMOL Molecular Graphics System, Version 2.0 Schrödinger, LLC).