Table 5.
Association between the ApoA1 polymorphism related to metabolic components and risk of arterial stiffness on the basis of the CAVI index.
| Crude OR (95% CI) | Adjusted OR (95% CI)a | ||
|---|---|---|---|
| Metabolic syndrome | GG | Reference | Reference |
| GA + AA | 0.54 (0.28–1.04) | 0.79 (0.36–1.46) | |
| p value | 0.681 | 0.375 | |
|
| |||
| Central obesity | GG | Reference | Reference |
| GA + AA | 0.72 (0.39–1.32) | 0.91 (0.47–1.76) | |
| p value | 0.298 | 0.792 | |
|
| |||
| High blood pressure | GG | Reference | Reference |
| GA + AA | 1.52 (0.83–2.78) | 1.85 (0.94–3.67) | |
| p value | 0.173 | 0.740 | |
|
| |||
| Hyperglycemia | GG | Reference | Reference |
| GA + AA | 0.69 (0.34–1.42) | 0.90 (0.42–1.91) | |
| p value | 0.323 | 0.791 | |
|
| |||
| Hypertriglyceridemia | GG | Reference | Reference |
| GA + AA | 1.09 (0.52–1.93) | 1.12 (0.55–2.27) | |
| p value | 0.978 | 0.737 | |
|
| |||
| Low HDL-C | GG | Reference | Reference |
| GA + AA | 0.474 (0.24–0.93) | 0.59 (0.24–0.88) | |
| p value | 0.030 | 0.041 | |
|
| |||
| High hs-CRP levelb | GG | Reference | Reference |
| GA + AA | 0.30 (0.16–0.57) | 0.28 (0.13–0.64) | |
| p value | 0.006 | 0.010 | |
aAdjusted OR calculated from the logistic regression adjusted for sex, age, BMI, smoking, and drinking. bGeometric mean of the hs-CRP level. ApoA1, apolipoprotein A1; CAVI, cardio-ankle vascular index; OR, odds ratio; CI, confidence interval; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high-sensitivity C-reactive protein.