TABLE 2.
Hazard ratio (HR) and 95% confidence interval (CI) of the association of fat and oils types, and risk of BC based on tertile of fat and oils
| Tertile 1 | Tertile 2 | Tertile 3 | ||
|---|---|---|---|---|
| Fat and oil types | HR (95% CI) | HR (95% CI) | HR (95% CI) | P trend |
| Total lipid | ||||
| Participants (number) | ||||
| Case/noncase | 430/139 575 | 454/139 551 | 541/139 464 | — |
| Pearson year | 1 523 368 | 1 543 497 | 1 611 960 | — |
| Crude | 1 (reference) | 1.08 (0.96‐1.23) | 1.04 (0.91‐1. 91) | .512 |
| Model 1 a | 1 (reference) | 1.14 (1.00‐1.30) | 0.97 (0.85‐1.11) | .653 |
| Model 2 b | 1 (reference) | 1.13 (0.99‐1.29) | 0.95 (0.83‐1.09) | .451 |
| Total fatty acids | ||||
| Participants (number) | ||||
| Case/noncase | 411/139 594 | 414/139 591 | 600/139 405 | |
| Pearson year | 1 539 499 | 1 527 401 | 1 611 925 | — |
| Crude | 1 (reference) | 0.96 (0.84‐1.11) | 1.16 (1.02‐1.31) | .015 |
| Model 1 a | 1 (reference) | 0.97 (0.84‐1.12) | 0.94 (0.82‐1.06) | .342 |
| Model 2 b | 1 (reference) | 0.96 (0.84‐1.11) | 0.90 (0.79‐1.03) | .161 |
| Saturated fatty acids | ||||
| Participants (number) | ||||
| Case/noncase | 376/139 629 | 463/139 542 | 586/139 419 | — |
| Pearson year | 1 523 593 | 1 565 893 | 1 589 340 | — |
| Crude | 1 (reference) | 1.18 (1.03‐1.35) | 1.23 (1.08‐1.41) | .002 |
| Model 1 a | 1 (reference) | 1.14 (0.99‐1.31) | 1.09 (0.95‐1.25) | .235 |
| Model 2 b | 1 (reference) | 1.12 (0.97‐1.28) | 1.04 (0.91‐1.20) | .583 |
| Mono‐unsaturated fatty acids | ||||
| Participants (number) | ||||
| Case/noncase | 485/139 520 | 448/139 557 | 492/139 513 | — |
| Pearson year | 1 526 609 | 1 546 260 | 1 605 956 | — |
| Crude | 1 (reference) | 0.91 (0.80‐1.04) | 0.82 (0.72‐0.94) | .004 |
| Model 1 a | 1 (reference) | 0.96 (0.84‐1.09) | 0.83 (0.73‐0.95) | .008 |
| Model 2 b | 1 (reference) | 0.98 (0.86‐1.11) | 0.84 (0.73‐0.96) | .013 |
| Poly‐unsaturated fatty acids | ||||
| Participants (number) | ||||
| Case/noncase | 426/139 579 | 434/139 571 | 565/139 440 | — |
| Pearson year | 1 516 905 | 1 535 911 | 1 626 010 | — |
| Crude | 1 (reference) | 1.08 (0.94‐1.23) | 1.23 (1.08‐1.40) | .001 |
| Model 1 a | 1 (reference) | 1.00 (0.88‐1.15) | 0.97 (0.85‐1.10) | .611 |
| Model 2 b | 1 (reference) | 1.01 (0.88‐1.15) | 0.96 (0.84‐1.10) | .604 |
| Total cholesterol | ||||
| Participants (number) | ||||
| Case/noncase | 409/139 596 | 482/139 523 | 534/139 471 | — |
| Pearson year | 1 582 561 | 1 545 622 | 1 550 642 | — |
| Crude | 1 (reference) | 1.11 (0.97‐1.26) | 1.17 (1.03‐1.33) | .006 |
| Model 1 a | 1 (reference) | 1.09 (0.96‐1.25) | 1.17 (1.03‐1.34) | .031 |
| Model 2 b | 1 (reference) | 1.11 (0.97‐1.26) | 1.27 (1.05‐1.37) | .017 |
Abbreviations: CI, confidence interval; HR, hazard ratio.
a
Adjusted for smoking status, age, gender and total energy intake in kilocalories.
b
Adjusted for model 1+ sugar and sugar products, beers, wine, dressing, vegetables and fruits.