Table 1.
Comparison of the median values from three exams based on the disease type: (a) all patients, (b) patients with endoscopic remission, (c) histological remission, and (d) complete mucosal healing
| Pancolitis | Left‐sided | Proctitis | P‐value † | |
|---|---|---|---|---|
| (a) All patients | n = 70 | n = 27 | n = 17 | |
| PGE‐MUM (μg/g·Cr) | 15.7 | 15.0 (26) | 15.1 | 0.911 |
| FC (mg/kg) | 54.3 (67) | 29.9 | 8.7 (15) | 0.002 |
| FIT (ng/mL) | 0 (68) | 0 | 0 (16) | 0.079 |
| (b) ER | n = 35 | n = 11 | n = 13 | |
| PGE‐MUM (μg/g·Cr) | 13.7 | 14.8 | 14.5 (12) | 0.738 |
| FC (mg/kg) | 37.5 (34) | 20.0 | 8.4 (12) | 0.014 |
| FIT (ng/mL) | 0 | 0 | 0 | 0.406 |
| (c) HR | n = 34 | n = 16 | n = 15 | |
| PGE‐MUM (μg/g·Cr) | 14.2 | 13.1 (14) | 15.1 | 0.728 |
| FC (mg/kg) | 34.1 | 16.9 | 8.0 (13) | 0.038 |
| FIT (ng/mL) | 0 | 0 | 0 (14) | 0.821 |
| (d) CMH | n = 28 | n = 9 | n = 13 | |
| PGE‐MUM (μg/g·Cr) | 13.9 (27) | 14.8 (7) | 14.5 (12) | 0.814 |
| FC (mg/kg) | 37.5 | 20.0 | 8.4 (12) | 0.021 |
| FIT (ng/mL) | 0 | 0 | 0 | 0.793 |
†
Kruskal–Wallis test.
The number of analyzed samples is shown in parentheses if it differs from the total number of each disease type in (a)–(d). Very few patients with right‐sided colitis were excluded from this analysis.
CMH, complete mucosal healing; ER, endoscopic remission; FC, fecal calprotectin; FIT, fecal immunochemical test; HR, histological remission; PGE‐MUM, prostaglandin E‐major urinary metabolite.