TABLE 1.
Characteristics | Data |
---|---|
Patients, n | 90 |
Females, n (%) | 55 (61.1) |
Age at baseline a , median years (range) | 53.5 (18–83) |
Duration of MG at baseline a , median months (range) | 7 (0–300) |
Follow‐up, median months (range) | 72 (range: 16–223) |
Therapy at baseline a , n (%) | |
None | 0 (0.0) |
Anticholinesterase monotherapy | 10 (11.1) |
Immunosuppressive drug therapy | 80 (88.9) |
MGFA classification at baseline a , n (%) | |
0 (remission) | 7 (7.8) |
I | 21 (23.3) |
IIA | 13 (14.4) |
IIB | 19 (21.1) |
IIIA | 10 (11.1) |
IIIB | 11 (12.2) |
IVA | 4 (4.4) |
IVB | 3 (3.3) |
V | 2 (2.2) |
Remission of MG after baseline a , n (%), median months (range) | 76 (84.4), 19 (2–139) |
Thymectomy, n (%) | 49 (54.4) |
Thymectomy before baseline a , n (%) | 13 (26.5) |
Thymectomy 0–12 months after baseline, n (%) | 34 (69.4) |
Thymectomy >12 months after baseline, n (%) | 2 (4.1) |
Thymoma, n (%) | 17 (18.9) |
WHO histological type of thymoma, n (%) | |
A | 0 (0.0) |
AB | 4 (23.5) |
B1 | 3 (17.7) |
B2 | 5 (29.4) |
B3 | 4 (23.5) |
C | 0 (0.0) |
Unknown | 1 (5.9) |
Staging of thymoma, n (%) | |
Early stage thymomas b | 12 (70.6) |
Advanced stage thymomas c | 2 (11.8) |
Unknown | 3 (17.6) |
Abbreviations: MG, myasthenia gravis; MGFA, Myasthenia Gravis Foundation of America; WHO, World Health Organization.
At baseline: first analyses of anti‐acetylcholine receptor antibody serum levels in the Maastricht University Medical Center.
Early‐stage thymomas: Masaoka‐Koga stages I and II/TNM < T3N0M0.
Advanced‐stage thymomas: Masaoka‐Koga stages III and IV/TNM ≥ T3N0M0.