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. 2022 Jul 22;162:107170. doi: 10.1016/j.ypmed.2022.107170

Table 2.

Components of wearable technology mechanism (n = 18).

Author (year) Data Extraction
Data Preparation
Model Comparisons Best Model (Type) External Validation Distinguish COVID-19 from another ILI
WT Data Input Feature Selection or Extraction Data Augmentation Internal Validation Data Labelling/Data Segmentation
Alavi et al. (2021) Fitbit, Apple Watch Overnight RHR NR NR NR NA RHRAD, CuSum, NightSignal, Isolation Forest NightSignal (Deterministic Finite State Machine) NR No
Bogu and Snyder (2021) Fitbit RHR NR Seven time-series data augmentation techniques Time series cross-validation 7 days before and 21 days after symptom onset were considered as infectious NA Long Short-Term Memory Networks-based autoencoder (LAAD) (Unsupervised deep learning) NR No
Cleary et al (2021) Fitbit, Apple watch RHR, sleep and steps NR NR NR 0–7 days after symptom onset as test periods RHRmetric, SLEEPmetric, STEPmetric, SENSORmetric SENSORmetric (Statistical Analysis) NR No
D’Haese et al (2021) Oura Overnight HR, HRV, RR, activity, sleep and symptom report NR NR K-fold cross-validation Label symptoms suspicious of viral-like symptoms NA Markov network and Association Rule Mining Algorithm (Supervised deep learning and unsupervised machine learning) NR No
Gadaleta et al. (2021) Fitbit, Apple watch RHR, sleep, activity and symptom report Feature Extraction NR k-fold cross validation NR NA CatBoost (Supervised machine learning) NR No
Hassantabar et al. (2021) Empatica E4 Galvanic skin response, Temperature, inter-beat interval, oxygen saturation and symptom report NR Synthetic data generation with the TUTOR framework Unspecified NR Naïve Bayes, Random Forest, Ada Boost, Decision Tree, SVM, k-NN, deep neural network model with grow-and-prune synthesis Deep neural network model with grow-and-prune synthesis (Supervised deep learning) NR No
Hirten et al. (2021) Apple watch HRV NR NR Bootstrapping Defined being symptomatic as the first day of a reported symptom NA Mixed-effect Cosinor model (Statistical Analysis) NR No
Liu et al (2021) Fitbit HR NR NR leave one subject out cross-validation NR CNN, MLPs, LSTM Contrastive CAE (Unsupervised deep learning) NR No
CAE, contrastive CAE
Lonini et al (2020) NR RR intervals, steps, RR and frequency spectrum of cough signals Feature Selection NR leave-one-subject-out nested cross validation Labelled snapshots as COVID-19 positive and negative NA Logistic Regression (Supervised machine learning) NR No
Miller et al (2020) WHOOP Overnight RHR, HRV and RR NR NR Unspecified Meeting or exceeding threshold was equivalent to classifying healthy or infected days as COVID-19 positive. NA Gradient boosted classifier (Supervised machine learning) NR No
Mishra et al. (2020) Fitbit HR and steps Feature Extraction NR NR Dates of symptom onset and diagnosis to define sick periods RHR-Diff, HROS-AD, CuSum CuSum (Statistical Analysis) NR No
Natarajan et al. (2020) Fitbit RR, HR, and HRV NR NR k-fold cross validation Data from 2nd to 6th day of symptom onset labelled as sick NA CNN (Supervised deep learning) NR No
Nestor et al (2021) Fitbit Night-time RR, RHR, HRV and symptom report Feature Extraction NR Time series cross-validation Days between self-reported symptom onset and self-reported recovery labelled as positive XGBoost, XGBoost and GRU-D XGBoost and GRU-D (Supervised machine and deep learning) Prospective evaluation Yes
Quer et al (2021) Fitbit, Apple Watch RHR, sleep, activity and symptom report NR NR Bootstrapping First date of symptoms to seven days after symptoms considered infectious RHRMetric, SleepMetric, ActivityMetric, SymptomMetric, SensorMetric, OverallMetric OverallMetric (Statistical analysis) NR No
Sarwar and Agu (2021) Fitbit RHR and sleep Feature Selection and Extraction Synthetic Minority Over-sampling Technique (SMOTE) k-fold cross-validation 14 days after the symptom onset was considered as the infectious period Naïve Bayes, Random Forest, Ada Boost, Logistics Regression, SVM, Gradient Boosting Classifier, LSTM Autoencoder Gradient Boosting Classifier (Supervised machine learning) NR No
Skibinska et al (2021) Fitbit HR and steps Feature Extraction Synthetic data generation with the TUTOR framework k- fold Stratified Cross-Validation NR XGBoost, k-NN, SVM, Logistic Regression Decision Tree Random Forest k-NN (Supervised machine learning) NR Yes
Smarr et al. (2020) Oura Dermal temperature NR NR NR “Symptom window” as each individual’s window of reported symptoms NA Minimum and maximum temperature threshold (Statistical analysis) NR No
Zhu et al (2020) Huami/Amazfit RHR and sleep NR NR NR NR NA CDNet – CatNN and DenNN (Supervised deep learning) NR No

Note. CAE = conventional convolutional auto-encoder, CNN = conventional neural network, HR = heart rate, HROS-AD = heart rate over steps anomaly detection, HRV = heart rate variability, ILI = influenza-like illness, k-NN = k-nearest neighbour, LSTM =Long Short-Term Memory Networks, MLPs = Multilayer Perceptrons, NA = not applicable, NR = not reported, RHR = resting heart rate, RHRAD = resting heart rate anomaly detection, RHR-Diff = resting heart rate difference, RR = respiratory rate, SVM = support vector machines, WT = wearable technology