Table 3.

Adverse events of grade ≥2 that occurred in >3% in either studied populations

Adverse events	NEPA (n=60)					Historical controls (APR) (n=62)
	Grade					Grade
	0	1	2	3	4	0	1	2	3	4
Alanine transaminase	60	0	0	0	0	60	0	2	0	0
Constipation	32	28	0	0	0	52	8	2	0	0
Cough	56	1	3	0	0	53	9	0	0	0
Dyspepsia	55	2	3	0	0	60	1	1	0	0
Febrile neutropaenia	60	0	0	0	0	57	0	0	5	0
Infections	58	0	2	0	0	62	0	0	0	0
Mucositis—oral cavity	21	37	2	0	0	43	15	3	1	0
Neutropaenia	37	2	12	2	7	27	0	14	8	13
Pain	57	1	0	2	0	62	0	0	0	0
Rectal haemorrhage	58	0	2	0	0	62	0	0	0	0
Upper respiratory infection	52	3	3	2	0	62	0	0	0	0