FIGURE 7.

Inflammation alters K_IR channel‐mediated haemodynamic responses and electrophysiology to whisker stimulation. (a) No effect of Ba²⁺ (10 μM) on haemodynamic responses to whisker stimulation in WT mice (n = 5). (b) Significantly reduced cerebral blood flow (CBF) and oxyhaemoglobin responses (peak HbO) in WT but not in TGF mice to whisker stimulation after superfusion with Ba²⁺ (100 μM). (c) Deoxyhaemoglobin (HbR) was reduced in TGF mice after Ba²⁺ superfusion. Conserved neuronal activity after superfusion with Ba²⁺ (100 μM) in WT mice but not in TGF mice (showing reduced θ, α and γ power). *P < 0.05 represent differences between baseline and treatment in Student's t‐test. Error bars represent SEM. n = 9 for WT; n = 10 for TGF.  HbT; total haemoglobin [Correction added on 20 July 2022, after first online publication: Figure 7 has been corrected in this version.]