TABLE 4.

Median (interquartile range) values of bone markers at baseline and after 12 weeks on modified Atkins diet in 53 patients divided according to median age 37 years, and 51 patients divided according to median BMI 25.82 kg/m²

	Age, n = 53		BMI, n = 51
	<37 years, n = 26	≥37 years, n = 27	<25.8 kg/m², n = 25	≥25.8 kg/m², n = 26
PTH, pmol·L–1
Baseline	4.04 (2.99)	5.04 (3.75)	3.96 (2.86)	5.11 (3.22)
12 weeks	3.43 (2.50)	4.55 (2.79)	4.12 (2.65)	4.24 (2.07)
p	<.01	.05	.96	<.01
Ca, nmol·L–1
Baseline	1.25 (.06)	1.23 (.06)	1.25 (.07)	1.36 (.06)
12 weeks	1.26 (.07)	1.22 (.05)	1.22 (.04)	1.22 (.05)
p	.01	.09	.04	.01
25‐OH vit D, nmol·L–1
Baseline	55.50 (26)	65 (30)	71 (40)	59 (25)
12 weeks	77 (34)	67.50 (26)	80 (28)	65 (30)
p	<.01	.24	.06	.02
1,25‐OH vit D, nmol·L–1	n = 25	n = 27
Baseline	103 (61.50)	95.00 (41)	88.00 (62)	100 (46)
12 weeks	84 (63)	93.00 (38)	83.00 (49.50)	93 (51)
p	<.23	.05	<.01	.55
Ph, mmol·L–1
Baseline	1.10 (.20)	1.10 (.20)	1.10 (.20)	1.10 (.25)
12 weeks	1.20 (.10)	1.20 (.30)	1.20 (.25)	1.20 (.20)
p	.24	.12	.16	.17
ALP, U/L
Baseline	57 (45)	67 (32)	65 (39)	70 (43)
12 weeks	64 (42)	64 (27)	59 (36)	64 (41)
p	.42	.12	.44	.09
CTX−1, µg/L
Baseline	.56 (.40)	.37 (.28)	.51 (.36)	.40 (.30)
12 weeks	.49 (.26)	.32 (.27)	.47 (.41)	.33 (.21)
p	.09	.12	.32	.02
P1NP, µg/L
Baseline	52.97 (40.35)	53 (24.80)	54 (34.56)	47.76 (24.85)
12 weeks	41.86 (37.67)	44 (34.29)	45.43 (39.11)	41.21 (26.83)
p	<.001	.07	<.01	.03

Abbreviations: 1,25‐OH vit D, 1,25‐OH vitamin D; 25‐OH vit D, 25‐OH vitamin D; ALP, alkaline phosphatase; BMI, body mass index; Ca, calcium; CTX‐1, C‐terminal telopeptide collagen type 1; P1NP, procollagen type 1 N‐terminal propeptide; Ph, phosphate; PTH, parathyroid hormone.