Table 3.

Formation of cyclic peptides in continuous flow.

Entry	Starting compound(s)	Coupling reagent(s)/ catalysts	Targeted structural scope	Solvent./T	Reactor	# Examples/ yields [%]	Ref.
1				MeCN 25 °C		1 36	[139]
		hν
2				DCM 25 °C		6 32–52	[140]
		DIPEA
3				DMF 25 °C		1 80	[141]
		DIPEA
4				DCM–DMF 60 °C		9 >95[a]	[73]

[a] Only conversions reported.