Table 4.

Peptidomimetics in flow.

Entry	Starting compound(s)[a]	Coupling reagent(s)/ catalysts	Targeted structural scope	Solvent/T	Reactor	# Examples/ yields [%]	Ref.
1				DMF–MeCN 20 °C		dimers: 2 74–98	[104]
		DIPEA
2				DMF 25 °C		trimers: 4 44–53 pentamers: 1 32	[105]
					H‐cube
3a		–		MeCN–MeOH 80 °C		8 80–95	[165]
4				DMF–MeCN–H2O 20 °C		4 70–83	[166]
		DMA
5		DIEA		DMF 60 °C		8 92–95	[167]
6		–		EtOH 80 °C		4 50–55	[168]

[a] Small blue reactor symbols close to substances indicate their in‐situ generation during the protocol.