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. 2022 Jan 18;130(3):415–422. doi: 10.1111/bcpt.13703

FIGURE 2.

FIGURE 2

Plot showing individual metformin concentrations during pregnancy and in the post partum period. Each dot represents a single measurement, corrected for time of ingestion. The lines represents mean metformin concentration (with 95% confidence interval) as a function of gestational length, according to a four‐parameter mixed logistic model with the inflection point set at 0 (i.e. birth). The left asymptote (mid‐pregnant) is 9.18 μmoL/L, and the right asymptote (non‐pregnant) is 13.24 μmoL/L. GW = gestational week, WPP = weeks post partum