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. 2022 Jul 22;7:248. doi: 10.1038/s41392-022-01034-7

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Distinguishable expression of embryonic and β-cell mRNA indices from naïve pancreatic exocrine cells isolated from donors. Abundance of Ins, Pdx1, Ngn3, Sox9 and Txnip mRNA. a Expression analyses in naïve exocrine cells showing the comparative abundance of mRNA relative to 18s assessed by qRT-PCR. Relative expression of mRNA isolated from non-diabetic (nd) and type 1 diabetic (T1D) donors. b Correlation of mRNA expression of Ins, Pdx1, Ngn3, Sox9 and Txnip displayed as a function of fold change. Expression analyses of mRNA isolated from non-diabetic (nd) and type 1 diabetic (T1D) donors. Significance is calculated by comparing nd1 v T1D and nd2 v T1D. Student t test, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Error bars represent SEM, n = 2