Table 8.
Group (Treatment) | % Wound Contraction# | |||||||
---|---|---|---|---|---|---|---|---|
Day 2 | Day 4 | Day 6 | Day 8 | Day 10 | Day 12 | Day 14 | Day 16 | |
Group 1 (SO) | 8.44 | 21.39 | 43.56 | 60.72 | 72.17 | 83.89 | 90.46 | 95.06 |
Group 2 (5% AFO) | 9.33 | 22.00 | 45.11 | 66.42 | 86.94 | 95.44 | 98.25 | 99.97 |
Group 3 (10% AFO) | 9.78 | 23.11 | 45.56 | 75.78 | 93.61 | 98.89 | 99.97 | 100.00 |
Group 4 (5% CFO) | 8.72 | 21.78 | 43.78 | 62.67 | 74.28 | 85.56 | 94.28 | 96.36 |
Group 5 (10% CFO) | 8.83 | 21.83 | 43.83 | 62.94 | 74.67 | 85.94 | 94.50 | 97.53 |
Group 6 (5% n-HFO) | 8.61 | 21.67 | 43.72 | 62.56 | 74.22 | 85.53 | 94.22 | 96.31 |
Group 7 (10% n-HFO) | 8.78 | 21.72 | 43.81 | 62.72 | 74.33 | 85.67 | 94.33 | 96.39 |
Group 8 (NFO 0.2%) | 9.22 | 23.00 | 45.44 | 74.22 | 92.00 | 98.58 | 99.78 | 100.00 |
Note: #% wound contraction is from the initial wound area (300 mm2).
Abbreviations: SO, simple ointment; AFO, aqueous fraction ointment; CFO, chloroform fraction ointment; n-HFO, n-hexane fraction ointment; NFO, nitrofurazone ointment.