Table 4.

Comparison of area under the curve values and accuracy of CA125 and/or HE4 vs. multiple biomarkers

	Biomarker set	Specificity (%)	Sensitivity (%)
CA125 vs. multiple marker set	CA125, HE4, CA15.3, ApoA1, ApoA2	96.18	88.11
	CA125	96.18	80.42
HE4 vs. multiple marker set	CA125, HE4, CA15.3, ApoA1, ApoA2	97.45	86.71
	HE4	97.45	69.23
CA125+HE4 vs. multiple marker set	CA125, HE4, CA15.3, ApoA1, ApoA2	93.63	93.71
	CA125+HE4	93.63	85.31

CA125, carbohydrate antigen 125; HE4, human epididymis protein 4; CA15.3, cancer antigen 15-3; ApoA1, apolipoprotein A1; ApoA2, apolipoprotein A2.